In this contributed article forThe Pathologist Proscia’s Dr. Monica Santamaria-Fries explores often-overlooked aspects of the digital transformation in pathology – the pathologist’s experience and the necessary cultural shift. She details how digitization is helping pathologists to achieve what matters most, including quality of care, efficiency, and wellbeing, helping to improve the pathologist experience in a way that aligns with healthcare’s quadruple aim. She also explains why driving the shift to digital requires hearing the pathologist’s voice, addressing any concerns, and delivering human-focused solutions that put the pathologist at the center.