Rupesh Mishra, Healthcare Solutions Architect, Amazon Web Services, and Coleman Stavish, CTO, Proscia
At Proscia, we’re committed to making digital pathology effortless, scalable, and enterprise-ready for our customers. That’s why Concentriq—our flagship enterprise pathology platform—is delivered as a cloud-native SaaS solution hosted on Amazon Web Services (AWS). Concentriq is architected to leverage AWS’s industry-leading security, scalability, and performance so our customers can focus on pathology and never have to manage their underlying infrastructure.
AWS is enabling Proscia to deliver a platform that meets the unique demands of modern digital pathology. When you choose Concentriq, you’re not just getting a software product. You’re getting a deeply integrated platform built from the ground up to take full advantage of the cloud.
Purpose-Built for Digital Pathology, Powered by AWS
Digital pathology is transforming life sciences and healthcare by digitizing slide-based workflows and enabling more accurate diagnoses, faster research, and new frontiers in AI-driven analysis. But realizing these benefits at scale requires more than just uploading images to the cloud. It demands a robust, secure, and purpose-built platform.
Proscia’s Concentriq is that platform.
Security and Compliance: Built In, Not Bolted On
By deploying Concentriq on AWS, Proscia inherits and implements AWS’s rigorous security and compliance standards, wrapping them in a platform that’s ready to use from day one.
- Data in Concentriq is encrypted at rest and in transit using AWS-native capabilities
- Role-based access control and integration with customer SAML SSO systems ensures PHI is protected
- Proscia’s use of AWS’s HIPAA-eligible services, combined with its ISO 27001 certification and ISO 13485–certified QMS, supports regulatory alignment across geographies
These capabilities are part of Concentriq’s foundation, not optional add-ons, so customers can onboard confidently, knowing that the infrastructure behind their data meets the most stringent requirements.
Performance and Scale without the Overhead
Digital pathology workloads are massive. A single whole slide image can exceed 1.5GB, and institutions often process hundreds of thousands of slides annually.
Rather than asking customers to estimate capacity, manage servers, or budget for storage tiers, AWS helps Concentriq handle this complexity behind the scenes:
- Elastic compute via Amazon Elastic Compute Cloud (Amazon EC2) Auto Scaling ensures consistent performance, even during peak workloads
- Amazon Simple Storage Service (Amazon S3) provides scalable, cost-optimized storage tuned for high-throughput pathology data
- AWS HealthImaging gives pathology teams low-latency access to petabyte-scale image archives, ensuring the right case is always available in seconds
- Managed services eliminate the need for infrastructure operations on the customer’s side
This allows Proscia to deliver exceptional performance to its users—whether they’re analyzing a single case or running AI inference across entire archives—without forcing them to touch the infrastructure.
Cost Efficiency: Optimized Behind the Scenes
One of the biggest myths in cloud computing is that “more flexibility means more cost.” In reality, smart architectural choices, like Proscia’s use of AWS storage tiers and automated scaling, mean its customers benefit from the cost efficiencies of cloud without the complexity of managing it.
For example:
- Concentriq leverages Amazon S3 storage classes to optimize costs for active and archival slide data
- It uses automated scaling and spot instances to minimize idle resource consumption and usage costs.
- It integrates with AWS HealthImaging to automatically move whole slide images between active and archive tiers
- Proscia’s team monitors usage patterns to continuously tune infrastructure for cost-performance balance
The result? An enterprise pathology platform that scales as you grow without unexpected bills or IT overhead.
Always-On, Always-Available
Downtime isn’t an option in clinical or research environments. Concentriq is built on AWS’s globally distributed infrastructure to deliver the high availability and disaster resilience that modern pathology workflows require.
With the most secure, extensive, and reliable global infrastructure spanning across 36 regions and 114 Availability Zones, with announced plans for additional ones in the future, AWS is the only cloud provider to offer three or more Availability Zones in all Regions, providing greater redundancy and better isolation to contain issues.
This means that Concentriq remains reliable, responsive, and robust—24/7:
- Multi-AZ architecture ensures failover and high uptime
- Disaster recovery strategies built on AWS Elastic Disaster Recovery (AWS DRS) help meet strict RTO/RPO requirements
- Monitoring and observability built on AWS services provide Proscia’s SRE teams with real-time insights
Ready for AI from Day One
With the rapid pace of AI innovation, it is critical that laboratories and life sciences organizations can build, deploy, and seamlessly integrate the algorithms they need across the digital pathology pipeline. Users running Concentriq on AWS can:
- Deploy and run AI models at scale with Amazon Elastic Kubernetes Service (EKS) and Amazon Elastic Container Registry (ECR) providing secure, high-performance storage for models, whether developed by Proscia, third parties, or internal teams
- Accelerate AI development by combining real-world and proprietary datasets with standardized formats from AWS HealthImaging, streamlining validation and regulatory readiness
- Access high-performance image data pipelines through AWS HealthImaging, which streams multi-billion-pixel pathology images as standardized DICOM inputs, ready for training and inference
- Benefit from GPU-backed compute provisioned on demand, ensuring advanced deep learning models run efficiently without manual infrastructure management
This unlocks advanced use cases like automated tissue classification, biomarker quantification, and high-throughput preclinical analysis, without the burden of AI infrastructure management.
A Better Cloud Experience by Design
At AWS, we’re committed to helping healthcare and life sciences organizations harness the power of the cloud without adding complexity. That’s why we work closely with innovative partners like Proscia, whose Concentriq platform is purpose-built on AWS to deliver the security, scalability, and performance that digital pathology demands.
AWS was awarded the 2025 Best in KLAS Award for Public Cloud, which our healthcare system customers have helped us earn through their trust in our services and customer experience. Feedback from our customers drive our innovation and commitment to excellence in healthcare technology.
With Concentriq on AWS, customers can gain a seamless path to digital transformation that’s grounded in proven technology and engineered to support real-world workflows at scale. Together, AWS and Proscia are accelerating the future of intelligent, cloud-powered pathology, today.
About the Authors:
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Rupesh Mishra is a Healthcare Solutions Architect at Amazon Web Services, specializing in machine learning and analytics. With over 15 years of experience spanning clinical and technical roles in healthcare, he is dedicated to enhancing patient outcomes through innovative technology. His expertise in digital pathology stems from his background as a Clinical Laboratory Scientist and Laboratory Informatics Specialist, where he led the implementation of various laboratory and pathology information systems. |
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Coleman Stavish is co-founder and CTO at Proscia. In his role, he works with a team of engineers and scientists who develop enterprise software in use at leading laboratories and pharmaceutical companies. Previously, in the earliest days of the iPhone and his software career, Coleman developed iPhone applications with over a million downloads worldwide. |

