Proscia Named Global 2026 Best in KLAS for Digital Pathology in EuropeFIND OUT WHY

Unlocking drug development’s greatest asset

Proscia Aperture™ surfaces patient insights at the moment of diagnosis, enabling biopharma companies to accelerate precision drug development and generate real-world evidence for market access strategies.

Powered by a global network of diagnostic labs reviewing 8M+ cases annually on the Concentriq enterprise pathology platform, Aperture helps to unlock the pathology data needed to advance novel therapies.

Concentriq AP: Annotated pathology slide with highlighted tissue regions, linked to a HER2-low breast cancer biomarker project.

The future of precision medicine starts with diagnosis

The Aperture solution transforms routine pathology diagnoses into real-time insights. Labs powered by Concentriq are well-positioned to elevate pathology’s role in precision medicine, and increase patient impact without changing a single workflow.

Academic medical centers, healthcare systems, and reference laboratories within our lab network are playing a bigger role in advancing novel therapies, and tapping into new opportunities for business growth.


The Proscia Aperture advantage

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Real-Time, Point of Diagnosis Insights

Surface patients within moments of earliest diagnosis – days to weeks before EHR or genomics alone. Notify providers before treatment decisions close enrollment windows.

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Diverse Global Diagnostic Network

Connect to a growing network delivering 8M+ diagnoses annually. Access the depth and diversity of a multimodal database with 12M+ digitized slides.

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Multi-Dimensional, AI-Enriched Data

Match patients with precision and build stronger evidence with comprehensive profiles from labs that include AI-enriched tissue images, AI-derived biomarkers, molecular results, clinical and genomic data.


How biopharma companies use Aperture to transform routine diagnoses into actionable intelligence

Proscia Aperture™: Workflow graphic showing a rich multimodal database integrating clinical, genomic, and imaging data to support clinical trials.

Delivering value across the precision medicine lifecycle

Frequently Asked Questions

What data sources does Aperture use to surface patient insights?
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Aperture analyzes diagnostic data captured through Concentriq, Proscia’s enterprise pathology platform, which powers a global network of digitized laboratories. It links to other testing and longitudinal records via tokenization to incorporate relevant clinical context and draws from a mix of structured and unstructured sources – including whole slide images, AI-enriched tissue, AI-derived biomarkers, molecular results, and genomic data.

How can anatomic pathology labs join the Proscia global diagnostic network that powers Aperture?
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Once your lab has adopted digital pathology with Concentriq, you’ll automatically gain access to the opportunities that Aperture delivers. Contact us today to learn about unlocking value with Concentriq and Aperture.

What makes Aperture different from other clinical trial recruitment approaches?
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Unlike EHR- or genomics-dependent platforms, Aperture identifies eligible patients within moments of pathology diagnosis — days to weeks earlier than competing approaches. Aperture’s patient profiles are comprehensive and built on unique data, unlocking rare or emerging cohorts critical to targeted therapy trials and strategies but invisible to conventional patient identification and surveillance methods. And because Concentriq sits at the heart of the diagnostic workflow, any additional testing or workup required can be executed by our diagnostic laboratory network.

Can Aperture match patients for rare or biomarker-driven trials?
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Yes. Drawing from a global diagnostic network processing 32,000+ daily diagnoses, Aperture provides the scale needed to identify even the smallest, hard-to-find patient populations. The AI interface enables sponsors to define complex inclusion and exclusion criteria through structured queries, delivering precise cohort matching.

What is the role of AI in powering Aperture?
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AI models on Concentriq power biomarker detection, image feature extraction, and diagnostic metadata analysis. These results, including quantified tissue morphology, visual phenotypes detection, and feature extraction for trial matching and real-world evidence, are all able to be queried on Concentriq. In addition, Aperture leverages AI to rapidly sift through tissue images, biomarkers, molecular results, and clinical records to match patients with the right trials and treatments, while also powering evidence for regulatory filings, diagnostic development, label expansions, and payer discussions.

How does Aperture help recruit representative populations and reduce bias in trial recruitment?
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Aperture sources data from a geographically and demographically diverse patient population from all care settings. This diversity in data helps sponsors improve trial representation, meet regulatory expectations, and design studies that better reflect real-world patient populations.

What types of data does Aperture use for trial or study matching?
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Aperture analyzes diagnostic and clinical data captured at the point of diagnosis to match patients against complex trial inclusion and exclusion criteria. This includes information derived directly from digitized slides and lab systems, as well as integrated clinical context from sources like EHRs and genomics. By drawing from structured and unstructured sources, Aperture provides a more complete view of each patient’s diagnostic profile — enabling precise, real-time trial matching.

Can Aperture support regulatory submissions and market access strategies?
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Yes. Aperture’s AI-enriched diagnostic data and biomarker monitoring insights can be used to generate regulatory-grade real-world evidence. Sponsors use this data to strengthen FDA and EMA submissions, support label expansions, inform payer negotiations, and accelerate market access for precision therapies. This data is delivered via Concentriq — the same enterprise platform that supports 16 of the top 20 pharmaceutical companies across discovery, development, and commercialization.

When is Aperture available?
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Aperture is available today for select Proscia Concentriq® customers. If you’re interested in early access or want to learn more about how Aperture can support your organization, please contact us at rwd@proscia.com.

Access Aperture

Aperture is now available to Proscia customers. Secure your place on the limited early access list today.

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